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4.2 新型抗躁狂药物
近年若干抗癫痫药也用于防止躁郁症的反复发作,而且颇有成效,使用较多者为卡马西平。卡马西平用治疗剂量(600~1 000 mg)的维持疗法也可同样减少躁狂或抑郁发作。对快速循环型躁郁症单独使用碳酸锂治疗无效者,也可试用小量卡马西平合并小剂量碳酸锂,以减少发作。此外,卡马西平近年用于治疗情感不稳定的人格障碍或癫痫人格者也卓有成效,使用安全。丙戊酸钠也具有与卡马西平的相似疗效,值得注意。
作者单位:北京安定医院,北京 100088
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