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慢性疲劳综合症的治疗

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1#
发表于 15-8-30 00:06:03 | 只看该作者 回帖奖励 |倒序浏览 |阅读模式
本帖最后由 mal 于 15-8-30 00:11 编辑

Among treatments that may be helpful for patients with chronic fatigue symptoms are these classes of drugs:

  • Antidepressants and benzodiazepines. Although not everyone with chronic fatigue syndrome is depressed, some antidepressants can help ease fatigue, pain, and disordered sleep. Cymbalta (duloxetine HCI--度洛西汀盐酸) is one of the most commonly prescribed antidepressants, followed by Effexor (venlafaxine---文拉法辛). The benzodiazepine Klonopin (clonazepam---氯硝安定) may also be used to help people sleep at night.
  • Anticonvulsants. For reasons that are not clear, medications typically used for prevention of seizures can sometimes help people with CFS. Lyrica (pregabalin---普瑞巴林) may be prescribed, especially for patients who also have fibromyalgia pain. Lyrica has been shown to reduce pain and physical discomfort in these patients.
  • Thyroid medications. Thyroid treatments can complement other treatments for people who are not responding as expected, especially if thyroid hormone levels are borderline. "Lots of times we will add thyroid pills to the mix if patients are not getting the response that we look for," says Papernik.
  • Stimulants. Provigil (modafinil---莫达非尼)or Nuvigil (armodafinil---阿莫达非尼) may be prescribed to increase daytime alertness. “Some people go so far as to use amphetamines,” says Papernik, although he does not recommend this approach over a long period.
  • Pain medication. For patients who experience severe headaches, joint pain, or other pain that is not managed with other treatments, pain medications may ease those symptoms.


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2#
 楼主| 发表于 15-8-30 00:16:22 | 只看该作者
scientists' theories that chronic fatigue syndrome could be caused by one or more of the following:

Infections. A variety of viruses, including Epstein Barr virus, some types of herpes viruses, and most recently the retrovirus XMRV, been linked to chronic fatigue syndrome.

Genetics. Some people may be more susceptible because of an inherited risk.

Neuroendocrinology. A complex interaction between neurotransmitters and hormones could be at the root of chronic fatigue syndrome.

Trauma
. The physical stress related to surviving traumatic events has also been identified as a possible contributing factor.
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3#
 楼主| 发表于 15-8-30 00:22:29 | 只看该作者
Some of the factors that have been studied include:

Viral infections. Because some people develop chronic fatigue syndrome after having a viral infection, researchers question whether some viruses might trigger the disorder.

Suspicious viruses include Epstein-Barr virus, human herpes virus 6 and mouse leukemia viruses. No conclusive link has yet been found.

Immune system problems. The immune systems of people who have chronic fatigue syndrome appear to be impaired slightly, but it's unclear if this impairment is enough to actually cause the disorder.

Hormonal imbalances. People who have chronic fatigue syndrome also sometimes experience abnormal blood levels of hormones produced in the hypothalamus, pituitary glands or adrenal glands. But the significance of these abnormalities is still unknown.
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4#
发表于 15-8-30 11:26:44 来自手机 | 只看该作者
这个帖子很全面了,谢谢!
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5#
发表于 15-8-30 11:36:34 来自手机 | 只看该作者
所以如果用抗抑郁药治疗的话,需要选多通道的,文拉法辛或度洛西汀,可是这两种药都用过了该怎么办……莫非真得回归三环……
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6#
 楼主| 发表于 15-8-30 13:52:13 | 只看该作者
我理解好像慢性疲劳综合症发展到一定程度,有可能引起抑郁焦虑等,抗抑郁药就是针对这些继发性的心理疾病,但对慢性疲劳综合症本身没有治疗作用吧?
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7#
发表于 15-8-30 22:13:09 来自手机 | 只看该作者
唉,现在都停留在假说阶段……
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