如果是Pyroluria这个病引起的抑郁,那就没必要吃抗抑郁药,补充锌和B6就好了。这不属于偏门治疗方法。精神疾病的诊断本来是要排除很多疾病后才能诊断的,只不过 ...
现在168 发表于 14-3-3 06:36
1、Pyroluria没有定义为某种病,是那些倡导 [size=1em]Orthomolecular psychiatry疗法的声称
精神病症状出现的一种现象的假说; 2、 Orthomolecular psychiatry的理论在美国20年代左右被提出,50年代由 Abram Hoffer为主要实践者,但在70年就已经被美国精神协会否定;
3、该理论无论从诊断到疗法从未被主流医学承认过,因此在美国被认为是偏方。
以下是资料来自维基:
Orthomolecular psychiatry is the use of orthomolecular medicine for mental illness. The approach uses unorthodox forms of individualized testing and diagnosis to attempt to establish an etiology for each patient's specific symptoms, and claims to tailor the treatment accordingly, using a combination of nutrients, dietary changes and medications that are claimed to enhance quality of life and functionality as well as to reduce or eliminate symptoms and the use of xenobiotic drugs.
Abram Hoffer in the 1950s was the first major practitioner. Hoffer's therapies focused on using niacin, among other nutrients, to treat what he diagnosed as acute schizophrenia based on an unaccepted test. In 1973, a task force of the American Psychiatric Association examined niacin monotherapy of patient populations with chronic schizophrenia and bipolar disorder and rejected the practice along with the reliability of Hoffer's diagnostic approach.[1]
History[ edit] Orthomolecular psychiatry began with Abram Hoffer and Humphry Osmond in the 1950s and was continued by Carl Pfeiffer of the Pfeiffer Treatment Center,[2] although proponents of orthomolecular psychiatry say that the ideas behind their approach can be traced back to the 1920s and '30s.[3][4] Orthomolecular psychiatry's goal of weaning patients from conventional neuroleptic drugs[5] follows "Pfeiffer's Law", "For every drug that benefits a patient, there is a natural substance that can achieve the same effect".[6] In 1968, Linus Pauling used the term "orthomolecular".[7][8]
The assertions by proponents of orthomolecular psychiatry were rejected in 1973 by a panel of the American Psychiatric Association.[1][9][10] Orthomolecular psychiatry has subsequently found little support in mainstream psychiatry.[11] After 1975, orthomolecular psychiatry research was primarily reported inOrthomolecular Psychiatry, now the Journal of Orthomolecular Medicine, a fringe publication founded by Abram Hoffer to counter what he considered to be a medical conspiracy against his ideas.[12]
Diagnosis[ edit] Proponents of orthomolecular psychiatry claim to have identified the causes of some psychiatric syndromes, in particular those that cause psychosis; according to orthomolecular proponents, testing for these causes guides diagnosis and treatment. Diagnostic measures and therapies commonly employed include "individual biochemical workup", fasting, identifying suggested allergies, dietary changes, megavitamin therapy, amino acids, and other so-called "pharmacologic nutrients".[5] These diagnoses have not been accepted by mainstream medicine.[11]
Specific conditions[ edit] Orthomolecularists claim that the causes of psychotic disorders include food allergy, hypoglycemia,hypothyroidism in the presence of normal thyroid values, heavy metal intoxications including those allegedly due to dental fillings, as well as several hypothesised conditions they call pyroluria,histadelia and histapenia.[5] These conditions are not recognized by the conventional medical community.
Pyroluria[ edit] Pyroluria (or malvaria from the term mauve factor) involves hypothetical excessive levels of pyrroles in the body resulting from improper hemoglobin synthesis.[13] Carl Pfeiffer believed that pyroluria is a form of schizophrenic porphyria, similar to acute intermittent porphyria where both pyrroles and porphyrins are excreted in the human urine to an excessive degree.[14] and orthomolecular psychiatrists have alleged that pyroluria is related to diagnoses of ADHD, alcoholism, autism, depression, down syndrome, manic-depression,schizophrenia, celiac disease, epilepsy, and psychosis.[15] Pfeiffer's methods have not been rigorously tested,[16] and pyrroles are not considered to be related to schizophrenia. Studies have either failed to detect hemopyrrole and kryptopyrrole in the urine of normal controls and schizophrenics, or found no correlation between these chemicals and mental illness.[17][18][19][20][21][22] Few, if any, medical experts regard the condition as genuine, and few or no articles on pyroluria are found in modern medical literature;[23] the approach is described as "snake oil" by pediatrician and author Julian Haber.[1
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