炎症是抑郁症的真正病因
本帖最后由 mal 于 14-6-7 11:48 编辑肠漏及炎症 如何影响大脑。肠道被称为我们的“第二大脑”。它包含神经系统组织（神经元），并产生更多的血清素 . 此外，脑和肠都从相同的胚胎组织发达。肠和脑是紧密相连的，因为它们彼此在胃酶，酸，胃血流量和消化速度的分泌通信。所以，当你有肠漏，毒素不仅加剧肠道内壁，但他们渗透到血液中，流动在你的身体和你的大脑。因此，肠道毒性等于有毒脑！与肠漏相关的各种炎症脑部症状是抑郁，焦虑，“脑雾”，精神分裂症，记忆力差，多动症，强迫症，读写障碍，老年痴呆症和自闭症。
How leaky gut and inflammation impact the brain. The gut is known as our "second brain". It contains nervous system tissue (neurons) and produces more serotonin.Also, the brain and gut both developed from the same embryonic tissue. The intestine and the brain are intimately connected in that they communicate with each other in the secretion of gastric enzymes, acid, gastric blood flow and the rate of digestion. So, when you have leaky gut, toxins not only inflame the gut lining but they leak into the blood stream, flow throughout your body and into your brain. Therefore, a toxic gut equals a toxic brain! Various inflammatory brain symptoms that are associated with leaky gut are depression, anxiety, "brain fog", schizophrenia, poor memory, ADHD, OCD, dyslexia, dementia and autism.
a leaky gut causes body-wide inflammation, including inflammation in the brain.
一个肠漏导致全身性炎症反应，包括炎症在大脑中。 炎症是抑郁症的真正病因。
肠漏导致炎症在大脑中引起抑郁症，并且还可能会导致炎症在其它器官系统，诸如冠状动脉导致升高的钙得分从冠状动脉疾病。
inflammation is the real etiology of depression.
The leaky gut causes inflammation in the brain causing depression, and may also cause inflammation in other organ systems such as the coronary arteries leading to elevated calcium score from underlying coronary artery disease. 如果一个人有自己的屏障系统遭到了破坏，他们将有一个增加的炎症反应。增加炎症反应增加所有慢性疾病的风险，包括抑郁症和神经变性疾病，心血管疾病，骨损失，自身免疫性疾病，炎症性肠道疾病和慢性疼痛。
If a person has their barrier system breached, they will have an increase in inflammatory response. Increases in inflammatory responses increase risk of all chronic disease, including depression and neurodegenerative diseases, cardiovascular disease, bone loss, autoimmune disease, inflammatory bowel disease and chronic pain.
某些炎症的化合物，称为细胞因子，分别提高了肠漏症，并直接与疲劳有关。如果你有慢性疲劳综合征，你的身体有可能产生高水平的针对毒素的免疫细胞通过肠漏症的不健康的肠道细菌的标志和炎症的病因释出。慢性疲劳症状的严重程度已经发现直接用针对毒素产生的肠道细菌的免疫细胞的血液水平相关。 你不健康的肠道细菌通过你的肠漏渗透越多，你极度疲劳和慢性疲劳的感觉更大
Certain inflammatory compounds, called cytokines, are increased by leaky gut syndrome and are directly
associated with fatigue. If you have chronic fatigue syndrome, your body likely produces high levels of immune cells directed against the toxins given off by unhealthy gut bacteria—a sign of leaky gut syndrome and a cause of inflammation. The severity of chronic fatigue symptoms has been found to directly correlate with blood levels of immune cells directed against toxin-generating gut bacteria. the more your unhealthy gut bacteria permeates through your leaky gut, the greater will be your feelings of extreme tiredness and chronic fatigue. 抑郁症，它是目前已知的肠漏激活肠道免疫系统产生的化学物质称为细胞因子，通过你的身体炎症扩散。炎症是抑郁症的症状，以及其他疾病，如疲劳，不适和疼痛的重要触发。
In depression, it is now known that leaky gut activates the intestinal immune system to produce chemicals called cytokines that spread inflammation through your body. Inflammation is an important trigger for depression symptoms as well as other maladies such as fatigue, malaise, and pain. 不会吧，炎症会抑郁，焦虑？消除炎症就没有抑郁焦虑了吗？可抑郁焦虑非常顽固，难以治疗 http://v.163.com/movie/2009/4/H/H/M868J41HT_M868Q94HH.html
抑郁症的病理生理学和治疗的炎症观点 貌似有一定的道理，抑郁症被有的专家认为就是脑部的炎症 看来，炎症和免疫系统的化学信使称为细胞因子的复杂集合在脑功能发挥重要作用，并可能导致心理症状。
It appears that inflammation and the complicated collection of immune system chemical messengers called cytokines play an important role in brain function and may cause psychological symptoms.
当大脑被任何紧张源，感染，外伤，中风，毒药，或营养缺乏加重炎症刺激促炎细胞因子的释放，这可能会影响心情。
When the brain is aggravated by any source-stress, infections, trauma, stroke, poisons, or nutritional deficiencies-inflammation spurs the release of pro- inflammatory cytokines, which may affect mood.
细胞因子激活的酶，吲哚胺2,3 - 双加氧酶（IDO），这会降低血清素,导致神经递质水平低。 IDO也降低了前驱体对血清素，色氨酸。神经递质血清素的水平降低可能促进抑郁症状的发展。炎症过程对血清素的恒定破坏 减小恢复的机会。
Cytokines activate an enzyme, indoleamine 2,3-dioxygenase (IDO), which degrades serotonin resulting in low levels of the neurotransmitter. IDO also degrades the precursor to serotonin, tryptophan. Decreased levels of the neurotransmitter serotonin are likely the contributing factor to the development of depressive symptoms. The inflammatory process' contribution to the constant destruction of serotonin decreases the chances of recovery. 本帖最后由 mal 于 14-6-8 03:45 编辑
How to 减少炎症和改善情绪：锻炼，减少压力，营养补充剂（即ω-3脂肪酸），以及优化的维生素D水平。
decrease inflammation and improve mood: exercise, stress reduction, nutritional supplements (i.e. omega-3 fatty acids), and optimizing vitamin D levels.
感染，压力，营养缺乏，和久坐的生活方式是炎症反应最常见的因素。
Infection, stress, nutritional deficiencies, and sedentary lifestyles are the most common factors.
一系列因素似乎增加抑郁症的发展的风险，似乎与全身炎症有关;其中包括心理压力，不良饮食习惯，缺乏运动，肥胖，吸烟，改变肠道的通透性，遗传性过敏症，牙齿烦恼，睡眠和维生素D缺乏。
A range of factors appear to increase the risk for the development of depression, and seem to be associated with systemic inflammation; these include psychosocial stressors, poor diet, physical inactivity, obesity, smoking, altered gut permeability, atopy, dental cares, sleep and vitamin D deficiency. 本帖最后由 mal 于 14-6-8 05:14 编辑
http://www.biomedcentral.com/1741-7015/11/200 本帖最后由 mal 于 14-6-10 01:09 编辑
炎症，就是平时人们所说的“发炎”，是机体对于刺激的一种防御反应，表现为红、肿、热、痛和功能障碍。炎症，可以是感染引起的感染性炎症，也可以不是由于感染引起的非感染性炎症。
如果是由感染引起的感染性炎症，可以使用一般人所说的“消炎药”或注射「消炎針」，实际上指的是抗生素，其實是殺死或抑制細菌的繁殖，而使感染引起的發炎減少。
如果不是由感染引起的炎症，医学上对于抑制炎症反应，用的是非類固醇抗發炎劑或類固醇。在中國大陸常说成“消炎藥”。
一、炎症的局部表现
4．痛：引起炎症局部疼痛的因素与多种因素有关。局部炎症病灶内钾离子、氢离子的积聚，尤其是炎症介质诸如前列腺素、5-羟色胺、缓激肽等的刺激是引起疼痛的主要原因。炎症病灶内渗出物造成组织肿胀，张力增高，压迫神经末梢可引起疼痛，故疏松组织发炎时疼痛相对较轻，而牙髓和骨膜的炎症往往引起剧痛；此外，发炎的器官肿大，使富含感觉神经末梢的被膜张力增加，神经末梢受牵拉而引起疼痛。
5．功能障碍：如炎症灶内实质细胞变性、坏死、代谢功能异常，炎性渗出物造成的机械性阻塞、压迫等，都可能引起发炎器官的功能障碍。疼痛也可影响肢体的活动功能。