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发表于 11-9-15 05:40:13
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本帖最后由 pengxc 于 11-9-16 09:10 编辑
有研究者认为,一些强迫症患者 -- 特别是在儿童中发现的一种类型 –-是由一种大家 熟悉的东西所致。被称之为“与链球菌感染相关的儿科自身免疫性神经精神障碍”,这种疾病有一个英文缩写名字,称为“PANDAS”。他们肯定这种强迫症是因为链球菌咽喉炎所致 -- 或更具体说,是因为抗链球菌的抗体所致。
如果他们是正确的,这注定是一个引人注目的的突破,证明细菌和至少一个类别的精神病之间有联系。如果细菌可以导致强迫症,那么抗生素就可以减轻或防止它 。
儿童精神科医生们早就知道,有时儿童的强迫症可以突然发病,像瘟疫一样,然后症状可以持续从几天到几个月或者更长。如果一般强迫症患者的典型症状是像一条正弦曲线(渐进型) -– 症状慢慢上升,逐渐达到高峰,然后再缓慢减弱。那么急性 强迫症患者发病的曲线图是锯齿型(突发型) -–先是 平面,然后骤然升高,接着相对急剧下降,然后再平面。
There are researchers who believe that some of this disturbing cacophony -- specifically a subset found only in children -- is caused by something familiar and common. They call it Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infection, or, because every disease needs an acronym, Pandas. And they are certain it is brought on by strep throat -- or more specifically, by the antibodies created to fight strep throat.
If they are right, it is a compelling breakthrough, a map of the link between bacteria and at least one subcategory of mental illness. And if bacteria can cause O.C.D., then an antibiotic might mitigate or prevent it -- a Promised Land of a concept to parents who have watched their children change overnight from exuberant, confident and familiar to doubt-ridden, fear-laden strangers.
Child psychiatrists have long known that sometimes O.C.D. in children can be like that, that it can come on fast, out of the blue, like a plague, and then last anywhere from days to months. If the typical graph of O.C.D. symptoms is a sine curve -- with episodes that ramp up slowly, peak gradually, then abate just as slowly -- the graph of rapid-onset O.C.D. is saw-toothed -- flat, then a sudden spike, followed by a relatively sharp drop, then flat again. |
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