Most experts recommend treatment with thyroid supplementation to achieve thyroid-stimulating hormone levels in the numerically lower end of the normal range, which is associated with enhanced thyroid function
最好可以把TSH维持在0.1
if a patient's mood symptoms don't respond to the usual treatments, or if a treatment that has been effective seems to lose its effectiveness, a thyroid problem, esp abnormally low thyroid functioning (hypothyroidism), should be suspected.