本帖最后由 mal 于 14-7-10 12:44 编辑
抗抑郁剂 < 安慰剂
For depressed people with bipolar disorder who are taking a mood stabilizer, adding an antidepressant medication is no more effective than a placebo
对于正在服用情绪稳定剂的抑郁的人(患有躁郁症),加入一种抗抑郁药物并不比加入安慰剂更有效
Of the 179 participants who received an antidepressant in addition to a mood stabilizer, 24 percent achieved a durable recovery (at least eight weeks with no more than two depressive or two manic symptoms), compared with 27 percent of the 187 participants who took a mood stabilizer plus placebo. Moreover, adding an antidepressant did not increase the risk of a switch to mania or hypomania. The similar rates of durable recovery indicate that the addition of an antidepressant medication to adequate, optimally dosed mood-stabilizing medications does not improve recovery from bipolar depression any more than adding a placebo.
收到抗抑郁药(+mood stabilizer)的179名参与者中,24%实现了持久的复苏 .
收到安慰剂(+mood stabilizer)的187名参与者中, 27%实现了持久的复苏 。
此外,加入一种抗抑郁药并不增加躁狂或轻躁狂的风险.
添加一种抗抑郁药物, 不会比加安慰剂更有效。
Bupropion (sustained-release formula) and paroxetine are commonly used for patients with bipolar-related depression.
安非他酮和帕罗西汀通常用于治疗双相相关的抑郁症。
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