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标题: 抗抑郁剂 < 安慰剂 [打印本页]

作者: mal 时间: 14-7-10 09:35
标题: 抗抑郁剂 < 安慰剂
本帖最后由 mal 于 14-7-10 12:11 编辑

STEP-BD is the largest treatment study conducted for bipolar disorder

The STEP-BD study enrolled a total of 4,360 patients l

asting five years

For depressed people with bipolar disorder who are taking a mood stabilizer, adding an antidepressant medication is no more effective than a placebo
对于正在服用情绪稳定剂的抑郁的人(患有躁郁症)，加入一种抗抑郁药物并不比加入安慰剂更有效

Of the 179 participants who received an antidepressant in addition to a mood stabilizer, 24 percent achieved a durable recovery (at least eight weeks with no more than two depressive or two manic symptoms), compared with 27 percent of the 187 participants who took a mood stabilizer plus placebo. Moreover, adding an antidepressant did not increase the risk of a switch to mania or hypomania. The similar rates of durable recovery indicate that the addition of an antidepressant medication to adequate, optimally dosed mood-stabilizing medications does not improve recovery from bipolar depression any more than adding a placebo.

收到抗抑郁药(+mood stabilizer)的179名参与者中，24％实现了持久的复苏 .
收到安慰剂(+mood stabilizer)的187名参与者中, 27％实现了持久的复苏。

此外，加入一种抗抑郁药并不增加躁狂或轻躁狂的风险.
添加一种抗抑郁药物, 不会比加安慰剂hao。

Bupropion (sustained-release formula) and paroxetine are commonly used for patients with bipolar-related depression.

安非他酮和帕罗西汀通常用于治疗双相相关的抑郁症。

作者: 方圆1 时间: 14-7-10 11:31
你这贴可能被删。我感觉你总喜欢搞一些奇谈怪论的文章。你是不是一直在吃安慰剂？

作者: 方圆1 时间: 14-7-10 11:32
外国我有极少唱反调的，写了这些文章，似乎我们也用不着热情替他们宣传吗？安慰剂有这么多的副作用吗？我明天要不要去加药？

作者: 方圆1 时间: 14-7-10 11:34
每门学术都有少数唱反调以扬名立万的，我们要识破他们，可以不用与他们过多纠缠。

作者: mal 时间: 14-7-10 11:57
本帖最后由 mal 于 14-7-10 12:22 编辑

方圆1 发表于 14-7-10 11:31
你这贴可能被删。我感觉你总喜欢搞一些奇谈怪论的文章。你是不是一直在吃安慰剂？

STEP-BD is the largest treatment study conducted for bipolar disorder
CONCLUSIONS

Of the symptomatic patients, 58% had remission within 2 years and 43% had recovery
50% of those who had remission had recurrence
Risk factors for recurrence: rapid cycling, anxiety disorder, residual symptoms, more lifetime episodes

作者: mal 时间: 14-7-10 12:13

方圆1 发表于 14-7-10 11:32
外国我有极少唱反调的，写了这些文章，似乎我们也用不着热情替他们宣传吗？安慰剂有这么多的副作用吗？我明 ...

要去加药

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