针药并用治疗抑郁症疗效观察
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发表日期:2005-01-24作者:林 虹 李根起 周正保本页面已被访问:78次
Clinical study on treatment of depression with combined acupuncture
and antidepressant.Lin Hong,LI Gen-qi,Zhou Zheng—bao,et al.(Tianjin Anding Hospital,Tianjin 300074,China)
[Abstract]Objective The aim of this study was to detelmine the effcacy and safety of using acupuncture combihed with nuoxetine hydrochlohde treating depressive patents.Methods A controlled study was carried out between 53 patients who met the CCMD-3 criteria of major depression and depressed episode.The 30 of total patients were treated with acupunctute combined with fluoxetine hydrochloride(10mg/d) and others were treated with simple fluoxetine hydrochllride(20mg/d) for 6 weeks.The effcacy were assessed by Hamilton Depression Rating Scale(HAMD),Hamilton Anxiety Scale(HAMA),CHinical Global lmpression (CGl) and the safety was assessed by Treatment Emergent Symptom Scale(TESS).Results After 6weeks treatment,the improvement rate and signficant improvement rate of acup
uncture plus fluoxetine hydrochloride group and fluoxetine hydrochloride group were 87%and 69%;86%and67%,respectively(P>0.05).The effcacy started after 7days treatment in acupuncture p1us fluoxetine hydrochlohde group.The scores of HAMD and HAMA in two groups were statical difference before and after treatment(P<0.01).There was no difference between two groups (p>0.05).There were lower side effects in acupuncture plus nuoxetine hydrochloride group than that in nuoxetine hydrochloride group.Conclusion Acupuncture plus antodepressant is an effective method which is suitable for chnlcal use.