Prescilla 发表于 14-7-14 05:30
不仅仅是度洛西丁，文拉法辛，帕罗西丁这三种药可以治GAD，医生给他推荐的来士普许多人用后效果也不错的， ...
who 夸大药物的副作用?
Prescilla 发表于 14-7-14 05:30
不仅仅是度洛西丁，文拉法辛，帕罗西丁这三种药可以治GAD，医生给他推荐的来士普许多人用后效果也不错的， ...
who 夸大药物的副作用?
如果百忧解能坚持下去，也许会好多了，还是回到吃百忧解吧
你这人既然知道药物如此重要，有的还很神奇，以后就少发点那些什么安慰剂更牛的文章。负责任点。在北美？混的不错吧？能不能把我也带出去？我英语也很好。试药要有点耐心，一般一个月是需要的。另外，一个药有效，要懂得珍惜。你不珍惜，回过头来，它就会给你颜色看。
楼主不是说了，人家老老实实吃了3年。
Prescilla 发表于 14-7-13 23:32
撤药反应也就一两周之内吧！超过2周症状还加重了那是停药后病情反复了，就是不到停药非停药，只能说自找的 ...
Many are finding out the hard way that Cymbalta is extremely difficult to stop using.
After dropping her dose from 60 mg per day to the next lower dose of 30mg per day, the nightmare began. The severe mood swings started. Her legs became increasingly restless. And she could not sleep. At first, I did not know what was happening to her. All of her blood tests were normal. But when she stopped the Cymbalta all together, WOW! She really started to go through hell. She began experiencing severe nausea, headaches, and an assortment of cognitive problems. That's when I knew that she was experiencing Cymbalta Discontinuation Syndrome.
A recent FDA advisory committee report about Cymbalta Discontinuation Syndrome states that there is "much anecdotal evidence" similar to this experience regarding the withdrawal syndrome that people experience when trying to get off of Cymbalta....
Doctors need to get detailed medication histories and know that this syndrome can last for months.
本帖最后由 mal 于 14-7-15 01:59 编辑
Prescilla 发表于 14-7-14 05:30
不仅仅是度洛西丁，文拉法辛，帕罗西丁这三种药可以治GAD，医生给他推荐的来士普许多人用后效果也不错的， ...
我和主人公一样？他一开始就吃３年药！我们太不一样了。我还没研究药物的付作用，只是在研究这个病。我真没觉得他夸大药物的副作用，他只是如实地写了他的用药感受.
欣百达的停药反应的确比其他药厉害。
Prescilla 发表于 14-7-14 05:30
不仅仅是度洛西丁，文拉法辛，帕罗西丁这三种药可以治GAD，医生给他推荐的来士普许多人用后效果也不错的， ...
我和主人公一样？他一开始就吃３年药！我们太不一样了。我还没研究药物的付作用，只是在研究这个病。我真没觉得他夸大药物的副作用，他只是如实地写了他的用药感受。的停药反应的确比其他药厉害。
Prescilla 发表于 14-7-14 05:30
不仅仅是度洛西丁，文拉法辛，帕罗西丁这三种药可以治GAD，医生给他推荐的来士普许多人用后效果也不错的， ...
我和主人公一样？他一开始就吃３年药！我们太不一样了。我还没研究药物的付作用，只是在研究这个病。我真没觉得他夸大药物的副作用，他只是如实地写了他的用药感受。的停药反应的确比其他药厉害。
哪里找到的帖子？
mal14-7-14 11:24
Many are finding out the hard way that Cymbalta is extremely difficult to stop using.
After dro ...
С顣潲1%óмоλ
Discontinuation of Treatment with Cymbalta
Discontinuation symptoms have been systematically evaluated in patients taking duloxetine. Following abrupt or tapered discontinuation in placebo-controlled clinical trials, the following symptoms occurred at 1% or greater and at a significantly higher rate in duloxetine-treated patients compared to those discontinuing from placebo: dizziness, headache, nausea, diarrhea, paresthesia, irritability, vomiting, insomnia, anxiety, hyperhidrosis, and fatigue.
During marketing of other SSRIs and SNRIs (serotonin and norepinephrine reuptake inhibitors), there have been spontaneous reports of adverse events occurring upon discontinuation of these drugs, particularly when abrupt, including the following: dysphoric mood, irritability, agitation, dizziness, sensory disturbances (e.g., paresthesias such as electric shock sensations), anxiety, confusion, headache, lethargy, emotional lability, insomnia, hypomania, tinnitus, and seizures. Although these events are generally self-limiting, some have been reported to be severe.
Patients should be monitored for these symptoms when discontinuing treatment with Cymbalta. A gradual reduction in the dose rather than abrupt cessation is recommended whenever possible. If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, then resuming the previously prescribed dose may be considered. Subsequently, the physician may continue decreasing the dose but at a more gradual rate
唉小姐别着急，给找来了英文说明书。里面讲严重的撤药反应的发生率也就1%或稍高点，这也不是不可接受的比例，经常还有人出门让车给撞死了，难道就不出门了。再者，说明书强调里了要缓慢停药，如若发生停药反应，要迅速恢复至原有剂量，然后以更缓慢的速度停药。不知道你的例子中举的哪位女士为什么不按照说明书停药。DiscontinuationofTreatmentwithCymbaltaDiscontinuationsymptomshavebeensystematically evaluatedinpatientstakingduloxetine. Followingabruptortapered discontinuationinplacebo-controlledclinicaltrials,thefollowingsymptoms occurredat1%orgreaterandatasignificantlyhigherratein duloxetine-treatedpatientscomparedtothosediscontinuingfromplacebo: dizziness,headache,nausea,diarrhea,paresthesia,irritability,vomiting, insomnia,anxiety,hyperhidrosis,andfatigue. DuringmarketingofotherSSRIsandSNRIs(serotoninand norepinephrinereuptakeinhibitors),therehavebeenspontaneousreportsof adverseeventsoccurringupondiscontinuationofthesedrugs,particularlywhen abrupt,includingthefollowing:dysphoricmood,irritability,agitation, dizziness,sensorydisturbances(e.g.,paresthesiassuchaselectricshock sensations),anxiety,confusion,headache,lethargy,emotionallability, insomnia,hypomania,tinnitus,andseizures.Althoughtheseeventsare generallyself-limiting,somehavebeenreportedtobesevere. Patientsshouldbemonitoredforthesesymptomswhen discontinuingtreatmentwithCymbalta.Agradualreductioninthedoserather thanabruptcessationisrecommendedwheneverpossible.Ifintolerablesymptoms occurfollowingadecreaseinthedoseorupondiscontinuationoftreatment, thenresumingthepreviouslyprescribeddosemaybeconsidered.Subsequently, thephysicianmaycontinuedecreasingthedosebutatamoregradualrate
每种递质如果补充过量都会有副作用，因为递质之间都有个互相平衡，有相互作用，这种递质多了就容易引起相关的递质被抑制而减少，出现相关的副作用，比如单纯补五羟色胺容易引起胃肠道反应，单纯补去甲肾上腺素容易影响心跳和血压。。等等。同时补充两种递质的抗抑郁药比如SNRI作用比较强效起效较快，适合中度以上抑郁，同时副作用也相对大些。
mal 发表于 14-7-15 07:10
每种递质如果补充过量都会有副作用，因为递质之间都有个互相平衡，有相互作用，这种递质多了就容易引起相关 ...
我吃的药都是没正作用也没副作用，立马停了也没反应，这是什么情况
也许楼主现在属于带有焦虑的轻度抑郁。
如果患者本人有还尚未意识到的或者说不愿意面对的焦虑源（潜意识层面），例如工作、生活方面的某些人某些事等等（童年阴影也可能属于这部分吧）。也许会不自觉地就吧焦虑源转移到其他方面如药物副作用上来了。打个比方，就好比某些普通人在领导那里受了气，结果回来对家人发无名火。
当然属于胡乱猜，90%的可能不属于这种情况，请莫介意。